CRISPR editing of mitochondria: Promising new biotech?

CRISPR editing of mitochondria: Promising new biotech?

CRISPR editing of mitochondria: Promising new biotech?

Although the CRISPR/Cas9 system has seen widespread application in editing the nuclear genome, using it to edit the mitochondrial genome has been problematic. The main hurdles have been a lack of suitable editing sites in the small mtDNA, and the traditional difficulty of importing the guide RNA into the mitochondrial matrix where nucleoids can be accessed.
CRISPR editing of mitochondria: Promising new biotech?